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Evidence grade lookup

Type a peptide name, brand or alias and get its evidence grade on the published A to D scale with the X flag for FDA safety concerns, what the grade applies to, the regulatory route with dates, safety signals on record, and every human study we cite with its PubMed id. Fourteen substances plus the GLP-1 peptides. No doses anywhere.

By FormBlends editorial teamAssumptions checked September 4, 2026Runs in your browser; nothing is sent to a server

Look up a peptide

Try BPC-157, TB-500, Egrifta, copper peptide, PT-141, NAD.

All entries

Result

Type a name or pick an entry. The result shows the evidence grade, what the grade applies to, the FDA and PCAC status, safety signals on record, and the human studies with PubMed ids.

Across the reference: 3 graded A, 1 graded B, 5 graded C, 6 graded D, and 10 carry the X flag for a published FDA safety concern.

Formulashown in full, nothing hidden
A = FDA-approved product with labelling for the graded use
B = two or more randomised controlled trials in humans for the graded use
C = one RCT, or only small controlled human studies, for the graded use
D = no controlled human study: animal, in vitro, observational, or uncontrolled human reports
X = FDA has published a specific safety concern for the substance in compounding

X is added when FDA has published a specific safety concern for the substance in compounding (the Category 2 page under section 503A or 503B, whether the substance is currently listed or shown as nominated but withdrawn), or when an approved product carries a warning of similar weight.

The grade is not a quality score and not a recommendation. It answers one question: what kind of human evidence exists for the use people ask about? Read the methodology page for the rules and their limits.

Assumptions, checked September 4, 2026

  • Regulatory status comes from FDA's 503A bulks page and category lists (May 14, 2026), the Category 2 safety-risk page (April 22, 2026), the PCAC meeting pages, Drugs@FDA and DailyMed. FDA moves substances between categories; the page date is the status date.
  • Studies are those we could locate in PubMed with the search terms shown on each peptide page. A count of zero means we found none, not that none can exist.
  • Studies of a related molecule (full-length thymosin beta-4 for TB-500, oral nicotinamide riboside for NAD+, epithalamin for epitalon) are shown but not counted toward the grade.
  • This tool contains no dosing information and none of the entries graded C or D is a medicine a pharmacy may lawfully dispense unless FDA's status changes.

This calculator is an arithmetic aid for medication a licensed prescriber has already prescribed. It does not recommend a dose. Confirm any result with your prescriber or pharmacist before use.

Read before you use it

Guides for this calculator

Educational, not medical advice. Read the medical disclaimer.